Blar i forfatter "Macqueen, Daniel J."

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    • Genome-Wide Reconstruction of Rediploidization Following Autopolyploidization across One Hundred Million Years of Salmonid Evolution 

      Gundappa, Manu Kumar; To, Thu-Hien; Grønvold, Lars; Martin, Samuel A. M.; Lien, Sigbjørn; Geist, Jürgen; Hazlerigg, David; Sandve, Simen Rød; Macqueen, Daniel J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-28)
      The long-term evolutionary impacts of whole-genome duplication (WGD) are strongly influenced by the ensuing rediploidization process. Following autopolyploidization, rediploidization involves a transition from tetraploid to diploid meiotic pairing, allowing duplicated genes (ohnologs) to diverge genetically and functionally. Our understanding of autopolyploid rediploidization has been informed ...

    • Phylogenetic Reclassification of Vertebrate Melatonin Receptors To Include Mel1d 

      Denker, Elsa; Ebbesson, Lars O.E.; Hazlerigg, David; Macqueen, Daniel J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-01)
      The circadian and seasonal actions of melatonin are mediated by high affinity G-protein coupled receptors (melatonin receptors, MTRs), classified into phylogenetically distinct subtypes based on sequence divergence and pharmacological characteristics. Three vertebrate MTR subtypes are currently described: MT1 (MTNR1A), MT2 (MTNR1B), and Mel1c (MTNR1C / GPR50), which exhibit distinct affinities, ...